The analysis of patterns of gene expression
Following the production of a 3D digital atlas of zebrafish development is a study of the genes and what expression patterns they have; here were refer to 3D patterns of gene expression studied by means of 3D imaging techniques. Our main focus is on using Confocal Laser Scanning Microscopy (CLSM).
Gene Expression Management System (GEMS)
The gene expression management system is designed and developed for the storage and retrieval of patterns of gene expression in zebrafish. [GEMS Browser]
Image Gallery
Some examples of patterns of gene expression as studied with the CLSM.
Fluorescent in situ Hybridisation
Some examples of patterns of gene expression as studied with the CLSM.
References
Top of page.Verbeek, F.J., Rodrigues, D., Siebes, A. Spaink, H.P.(2004) Data submission of 3D image sets to a bio-molecular database using active shape models and a 3D reference model for projection. Proceedings SPIE 6304, Internet Imaging V,
Verbeek, F.J., den Broeder,M.J., Boon, P.J., Buitendijk, B., van Raaij, E.J., Doerry, E., Zivkovic, D. (2000) A Standard 3D digital Atlas of Zebrafish Embryonic Development for Projection of Experimental Data. Proceedings SPIE 3964, Internet Imaging I, 242-252.
Verbeek, F.J., Lawson, K.A., and Bard, J.B.L. (1999). Developmental BioInformatics: linking genetic data to virtual embryos. Int.J.Dev.Biol. 43, 761-771.